Cancer-related pain
Cancer can cause pain all on its own, as tumors grow and take over formerly healthy areas of the body. The cancer can put pressure on organs, nerves, and bones, causing aching or sharp, stabbing pain. Some types of cancer even secrete certain chemicals that can cause painful sensations.
Your healthcare team can help determine the best course of treatment for managing pain. This may include over-the-counter pain relief options, prescriptions, or a complementary therapy.
Bone complications
Breast cancer commonly spreads to the bones, which can lead to a few complications. These complications are often caused by bone resorption, a normal process of breaking down bone. In healthy young people, bone is rebuilt at the same rate as it is broken down. In older adults and those with metastasis to the bones, the resorption process occurs more rapidly.
Bone pain
A painful, aching feeling in your bones is often the first sign that cancer has spread to the bone. As the condition progresses, resorption causes a thinning and weakening of the bones. When the bones become too weak, fractures can occur, sometimes without any major injury causing the damage.
Spinal compression
When cancer cells grow in or near the spine, they can put pressure on the spinal cord and adjacent nerves. This pressure can cause pain in the back or neck, numbness or tingling, and difficulty walking. Sometimes, it can lead to difficulty controlling the bladder and bowels. Spinal compression is less common than other bone complications, but it can be very serious.
Hypercalcemia
Hypercalcemia refers to elevated levels of calcium in the blood. This occurs when the rate of resorption increases, and calcium from the bones is released into the bloodstream. Hypercalcemia can lead to serious problems, such as:
kidney stones
kidney failure
irregular heartbeat
neurological problems, including confusion, dementia, or coma
Treating bone complications
A certain class of drugs, called bisphosphonates, works to slow the rate of resorption. These drugs work by destroying osteoclasts, the cells responsible for resorption. This helps to lower blood calcium levels, slow the weakening of bone structure, and lessen bone pain.
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